Potential Side Effects Covid-19 Vaccine

Vaccine Adverse Effects

It wouldn’t be invalid if I say that the year 2020 will be remembered as “COVID YEAR” in history. We as a generation saw this story unfold from the wet markets of WUHAN’S, China and in every area in every country of this world. It has been more than 1 year of this pandemic which has had a disastrous effect on earth.

With more than 92 Million cases, and 2 Million deaths, this pandemic is not stopping anyway. This virus is growing in most of the regions and countries that had visible success in defeating the initial outbreaks and are also seeing a rise in infections again.

The World Health Organisation (WHO) has informed that the virus will pursue to spread speedily in the coming months. Several European countries observed a growth in cases during the autumn. Most of the countries executed lockdowns and other restrictions to curb the infections. The United Kingdom is also facing another steep rise in cases driven by a new, more easily transmitted, mutated variant of the virus.

Various Coronavirus vaccines have now been authorized to be used, either by particular countries, or by European Union and WHO. There are currently more than 50 Covid-19 vaccines candidates in trials. Presently, there are two vaccines, authorized and suggested for covid-19. The Pfizer-BioNTech covid-19 vaccine, Moderna’s covid-19 vaccine.

As of 28 December 2020, large-scale phase 3 clinical trials are in progress for three covid-19 vaccines. In the United States are AstraZeneca’s Covid-19 vaccine, Johnsen’s Covid-19 vaccine, Novavax’s Covid-19 vaccine.

Covid-19 vaccines help our body prosper immunity to the virus that causes covid-19, without us having to get the sick. Several sorts of vaccines work in various methods to give shield, but with all sorts of vaccines, the body is deserted with supply of “Memory” T-Lymphocytes, B-lymphocytes as well as antibodies, that will remind how to fight with viruses in the future. It basically requires a few weeks for a body to construct T-Lymphocytes and B-lymphocytes after the vaccination.

Sometimes it is possible after vaccination, the process of enhancing the immunity can cause symptoms, such as fever, muscle pain, fatigue etc. These symptoms are common and are an indication that the body is constructing immunity.

such as fever, muscle pain, fatigue etc. These symptoms are common and are an indication that the body is constructing immunity.

So, it is very important that you understand the minor side-effects of covid vaccines. Also, we will discuss some of the rare but serious complications that can occur. Also, we will talk about whether you can get Covid-19 from covid vaccine? So, without further delay, let’s begin.

Common Side Effects

The most common side-effects you can experience after covid-19 vaccine includes

pain at the injection site
tiredness
headache
muscle pains
chills
Lymphadenopathy
fever, joint pains, swelling at the injection site
redness at the injection site and even also experience some kind of nausea.

Well, these are known as minor or expected side effects of vaccines and they can occur not just after Covid-19 vaccine but in fact after most of the vaccines that you receive. These side effects take place because your body is adapting to the vaccine.

You see, vaccines work by introducing a small amount of bacteria, virus or toxins into your body. Because of the bacteria, virus or toxins has been killed or weakened. There is no risk in contracting the disease in question. However, your body reacts as if it were under attack, and mounts an immune response.

If, in the future you do encounter the disease, you’ll have an army of cells and antibodies ready to fight it. This means that any disadvantageous effects you experience are unlikely to be start by the virus, bacteria or toxins in the vaccine. Most of the common side effects such as redness or fever cause by the injection or by your own immune system fighting against the weak invaders.

Chance of Serious Side Effects?

Serious adverse events, while possible, are very rare. Let’s understand by the example of yellow fever that is also generated by a virus. In conformity with the World health organization(WHO) , captious reactions happen at the figure of nearly 0.09 to 0.4 cases per 10 thousand doses of the yellow fever vaccine, in a community who haven’t been revealed to the virus. By contrast, the crucial form of yellow fever is fatal nearly half the time.

Rate of Serious Adverse Effects –

On an analogous note, the rate of serious allergic reactions is around 1-2 cases per million across all vaccines. Correlate that with the death rate of measles (around 1 in 500), and for flu which causes around 200 deaths in the UK alone, every winter, and it’s undeniable which is riskier.

What we require to realize are the risks and advantages – how many people are dying from yellow fever; how many people are dying from measles VS how many died from any serious adverse effects of the vaccine.

Clearly, adverse effects are devastating for the individuals and the family but they are rare, and we need to balance this with the risks correlated with that disease. So, there is a remote chance that covid-19 vaccine can cause a critical allergic reaction.

A critical allergic reaction would normally occur within a few minutes to one hour after getting a dose of the COVID-19 Vaccine. For this reason, your vaccination contributor may ask you to stay at the place where you received your vaccine for watching after vaccination.

Signs of a severe allergic reaction can include: Difficulty in breathing, swelling of your face and throat, A fast heartbeat, A skin rash all over your body, dizziness and extreme weakness.

Can the COVID Vaccine give me COVID-19?

“Big NO” is the answer to this question. None of the COVID-19 Vaccines contain SARS-CoV-2 virus, so it is possible that you can contract Covid-19 from the covid vaccine.

So, this was all about the side effects of Covid-19 vaccine. For more latest updates on CoronaVirus, stay updated on our blog.

Also Read How CoronaVirus Vaccines Work?

How CoronaVirus Vaccines Work?

How to Recover From Covid-19?

In this blog we will understand how Coronavirus attacks our body and how it makes us die? How the Coronavirus Vaccine Defeats virus? How does a man recover from a vaccine? Which vaccine is most effective? Which vaccine should we get? This is all you will get to know from this blog. Let’s start!

As you all know, corona spreads while we come into contact with any other infected person. The major term for this transmitting is “Droplets”, that’s why it is advised to maintain physical distancing. Outside the coronavirus, it has 2 parts. The protruding sharp part which is called spike protein is the deadliest. If it is removed then it will be of no use. And there is a bunch inside it that is called genetic material. It helps to enter our body.

Genetic material gives birth to new offspring like her. When this one virus will make one lakh viruses after going inside, we don’t even expect it. Spike protein is to and gets entered into our body and genetic material is to increase the number of viruses in the body.

The spike protein of this coronavirus is the only one that can touch the lungs and not the cells. Lungs cells are very sensitive. The cell membrane that is in the lungs also cannot enter from it.

The cell membrane allows certain things inside itself such as protein vitamins. And for something new that is taken from outside. They have receptors to go. This spike protein of the coronavirus sticks to this receptor and through it goes.

After entering, he gives his genetic information. This goes only on lungs because lungs tissues and cells are more sensitive. Our lungs receptor attracts spike protein and lets it go through our body which is more dangerous.

After going in, its genetic material which is RNA, it goes inside and matches with our DNA. Getting entered our lungs reach the nucleus of our body. After that it reaches the ribosome which is responsible for increasing the cell like proteins, vitamins and others. As the corona virus genetic material reaches the ribosome, the ribosome starts to double the virus; this process is known as replication.

When the immune system observes this replication, it starts fighting the virus and it keeps fighting. This is the main reason why we suffer from tiredness and fever in this disease. In this case our antibody works as a defence mechanism.

Antibody starts getting attached to the spike protein of the coronavirus and makes it lock so that the virus could not go inside through receptors. The only way we can fight with this virus is to keep our immune system strong so the antibodies can cover the spike protein and the virus did not enter our body.

What Vaccines do?

Vaccine is responsible to make antibodies within our body to fight with the virus. Vaccine contains chemicals to increase antibodies. The reason behind why this vaccine took so much time to invent is that the coronavirus has RNA which is made up of single helix whereas our body is made up of DNA which is double helix structure. RNA is easy to produce rather than DNA.

Types of Vaccines?

Many countries made their own vaccines like Pfizer is from America which has to be placed under -70-degree temperature which is not possible and have more side effects. Russia has the SPUTNIK vaccine, UNO invented the NOVAVAX vaccine for poor countries like Africa. Vaccine made by University of Oxford and AstraZeneca is named as “Covishield” in India. These vaccines are based on RNA. Vaccine made by Bharat Biotech in India is named as “COVAXIN”.

All the vaccines are functional. But only 60 to 70 percent of the vaccine is effective. It is not necessary that the vaccine will not cause corona, even if you are vaccinated. But the chances are rare, and the person will get cured at home and will not die.

Coronavirus vaccine dose will be applied 2 times and both will be different in 28-40 days. So that your body will be ready to make antibodies to fight this virus.

Now comes to the side effects of this vaccine! Well, there are no major side-effects of any of the vaccines. 90% of the people do not have any side effects whereas the other 10% faced common symptoms like fever, headache and tiredness for some interval of time. So go and get vaccinated!

This is all about the vaccination of Coronavirus stay updated to our blog for latest updates.

Also Read – Virafin a Hope to Abolish COVID-19

Second Wave of Covid 19 In India

What is Second Wave of Corona Virus?

Coronavirus pandemic started early in 2020, people even experts wondered if there would be waves of this coronavirus, or a pattern seen in other virus pandemics. The Second Wave has been increasing COVID-19 cases. Some of the locations have the highest number of infected cases and are increasing day by day.

The India and United States is the only country in the world which have reported 100,000 cases per day in the recent week. No other country had gone so far summing these many cases for two consecutive days.

When the second wave has hit India the coronavirus cases per day are increasing abruptly. On the 1st of February, India has reported around 11,427 covid-19 cases. In nearly 60 days the figure reached 70,000 on 1^st April. However, this count went from 70,000 to over 300,000 in just 20 days.

Reason Behind Sudden Peak in Corona virus Cases?

Humans are the major reason responsible. State government and local governments, also individuals are the reason behind this pandemic. Only some of the people are serious about the COVID- 19 precautions like physical distancing, wearing masks, washing hands frequently. While the other people are not as authoritarian in needing these measures or in limiting certain high-risk activities.

In nearby cities, towns and communities, public places are closed or practicing limitations like night curfew, weekends total lockdown; or some others are operating normally. Some government leaders also encourage people to wear masks and maintain physical distance in public areas. But some others say it is just a matter of personal choice.

However, the connection between these precautions and increasing cases of COVID-19 is clear: In areas where less people are wearing masks, do not maintain physical distance and gather more to eat, drink, religious practices, celebrate and socialize, even with their family, cases rising every single day.

Is COVID-19 Bad in Winter or in the Fall?

In the starting of the pandemic, some experts speculate: Will the COVID -19 go away in the summer? Unluckily, there is a spike during the hot summer months in India. made it clear that this is not the matter. Other respiratory problems, like colds and flu, are very common in the winter. Now that hot months are here, we are observing a substantial growth in COVID-19 across India. In winters there is a risk for further transmission of the virus.

Failed Prediction by IIT and ISI –

When the COVID 19 pandemic was extensive last year across India, the government had hired a committee of specialist from the Indian Institute of Technology and the Indian Statistical Institute. This committee predicted that the Covid-19 pandemic will come to an end in February 2021 in India due to herd immunity.

What is Herd Immunity?

Herd immunity refers to the reality that, when adequate humankind in a faction has immunity from this disease, the nation is safe from disruption of the disease.

Experts say that about 70% of the citizens require to be immune to this coronavirus before herd immunity performs. Residents may be immune from the COVID-19 Virus, for a while. An extensively accessible, safe and efficacious vaccine may not be available for a longer time.

Experts say if we let the coronavirus spread openly between the public it will result in thousands of deaths and millions of people left with lung, heart, brain or kidney damage.

Researchers are presently trying to discover if, and for how long, citizens are immune from the coronavirus after recovering. If it is results out that immunity only lasts for some time, it is possible that people can get COVID-19 again, which turns out even more death.

Researchers also predicted using some of the mathematical models that the ruthless second wave will be at peak by mid of April and May, will end by May.

Most of the Indian cities are reporting a continuous shortage of hospital beds and ventilators. Suffering and painful reports of people dying without getting treatment on time are coming from all over India.

Many state governments are trying their best in creating new facilities but doctors say it’s going to be very hard to keep up with the rate of the increasing count of coronavirus patients.

Most poorly -affected cities like Delhi, Mumbai and Ahmedabad have nearly run out of hospital beds and ventilators.

How to Calculate Peak of COVID19?

The Super model predicted by the experts has three vital variables to determine coronavirus pandemic. “The foremost variable is called Beta, or in an easy way we can call it contact rate, which calculates how many residents are infected everyday. It is linked to the R-naught value, which is the count of the infected person transmitting the virus.

The second variable is ‘Reach’, which calculates the exposure stage of the residents to Covid-19.

The third variable is ‘Epsilon’, fraction of traced and untraced coronavirus cases.

Many Doctors said that ‘Reach’ had to be commenced because of non-identical other pandemics that begin at a location and speedily spread, COVID-19 expanded slower because of some safety measures. ‘Epsilon’, on the other side, helps in the count of symptomless infections of covid 10 all over the country.

As now the spotted cases are isolated, we predict that there will be no longer transmission to new infections. So, an increasing count of per day new patients, reflects more unspotted infections. By calculating the number of new patients of coronavirus every day, we will try to predict the unspotted and symptomless infections.

Here’s are some precautions of what we can do now:

Continue precautions like physical distancing, hand-washing and mask-wearing.
Be in touch with local health authorities, who can offer guidelines if COVID-19 cases rise up in your city.
Try to maintain two weeks home supplies like food and prescription medicines.
Stay in touch with your doctor to make sure that everyone in your house get vaccine as fast as possible.

So, this was all the updates of Vicious Second Wave Coronavirus in India. Stay updated to our blog to get more information about Covid- 19 Test, Vaccine and many more.

Also Read Covid-19 RT PCR Test | What is CT Value?

Covid-19 RT PCR Test | What is CT Value?

RT-PCR Test Process

As we know, the Covid19 pandemic is rapidly growing worldwide, and there are an ascending number of cases of COVID-19 globally. Because of this there’s a rise in discussion of the certain medical terminologies that are used for the detection of COVID-19 like RT-PCR test, TruNat test, Serology blood test, antibody test and many more. By the statement of regulatory authorities like FDA, Food & Agriculture Organization of the United Nations (FAO), RT-PCR (Reverse Transcription Polymerase Chain Reaction) is considered as one of the most specific laboratory testing method to detect current Covid19 Virus.

In Addition, there are also other tests also used to detect the existence of the virus in peoples. Thus, with a growing count of individuals getting infected with this disease there’s a rise within the number of persons getting tested for RT-PCR Test. In many states, New Delhi as well it’s free of cost and needs no prescription for the testing.

RT-PCR Test for Covid 19?

PCR represent Polymerase chain reaction was introduced to spot a little fragment of virus and make multiple copies, making detection easier. PCR is ideal in examining COVID-19 virus and other viral diseases. Learn how this test works.

RT-PCR Test represent Reverse Transcription Polymerase Chain Reaction. It is a molecular form symptomatic testing method. An RT-PCR is a laboratory test that unite Reverse Transcription of RNA into DNA for the detection of covid-19 virus. (RT)-PCR test is recommended by WHO, using for the detection of COVID-19 virus. This test can quickly tell if someone accommodate the virus (5 to 7 hours). Researchers use an enzyme that transform the genetic material RNA within the virus to DNBA through a process known as Reverse Transcription. An RT-PCR test procedure uses throat or nose swabs to spot COVID-19 viruses. It also detects the virus even if the load is less.

RT-PCR is the leading and sensitive method for mRNA detection. It discloses the presence of a specific genetic material of the virus or any pathogen. RT-PCR is filled with fluorescent dyes as markers. RT-PCR helps researcher to examine the results at once.

The vital benefit of this RT-PCR testing procedure is its ability to give instant results.

Why Take Covid 19 RT-PCR Test?

Well, there is no particular vaccine or specific treatment for COVID-19. Some Medical care sure can help to relieve the symptoms. Antibiotics typically do not work in reverse to viruses; they only work out on bacterial infections. COVID-19 is generated by a virus, so antibiotics don’t work. Hence, antibiotics will not be used as prevention or treatment of COVID-19. They must only be used under supervision by a physician to treat a bacterial infection.

If you’re not in a locality where COVID-19 is transmitting, or if you’ve not travelling from one of those areas or haven’t been in close contact with someone who has and is feeling not well, your possibility of getting it is low for now. However, it’s acceptable that you might be feel disturbed and anxious about things going around. It’s a genuine idea to urge the facts to help you determine your risks so as that you’re going to take rational precautions.

In the middle of a surge in COVID-19 cases, the Maharashtra government earlier in the week had demanded the Centre to reduce the cycle threshold (CT) value cut-off from 35 to 24 for positivity rate of the RT-PCR test. They had asked to reduce the CT value for a lesser count of patients who come under the positive group.

But some Days later, the Indian Council of Medical Research (ICMR) denied the Maharashtra government’s request. While replying to them, the ICMR said, “performing a CT value cut-off of 24 isn’t advisable, as this may cause missing of many infectious patients and enhance disease transmission. CT value threshold helps to spot whether a patient is COVID positive or not.”

How to Calculate CT Value?

The calculation of CT Value suggests igenetic Diagnostics’ that offer Cycle Threshold (CT) value on Reverse Transcription-Polymerase Chain Reaction (RT-PCR) test reports. When the sample is taken from the patient, RNA is extracted and treated with a polymerase enzyme. A complementary DNA is pull off from an initial RNA. Next, the DNA can effortless be raise by engaging a polymerize chain reaction to make billions of copies of a fraction.

The DNA calculate in real time by fluorescein signals, through which it helps to measure the CT Value. Meantime, within the exponential stage, fluorescent signals data is pull off which is that the initial amount of the target DNA. Keep in mind: LOWER the CT VALUE equals to HIGHER viral load and HIGHER CT VALUE equals to LOWER viral load.

Pulse Oximeter detect COVID-19 at Home

The Pulse Oximeter is basically used in emergency rooms and hospitals in critical care. The pulse oximeter is a small device looks like a clip bind to a part such as toes or an earlobe. It most likely placed on a finger.

Pulse oximeter is basically a painless and bloodless test and that helps to calculate person oxygen saturation level, or the oxygen levels in your blood. It can instantly spot even little changes. It shows how smoothly oxygen is being carried to the limit furthermost from your heart, counting the legs and the arms as well.

The aim of pulse oximeter is to calculate how good your heart is pumping oxygen through your body.

Summary

At last, RT-PCR test is the centrepiece in determining COVID-19. The Reason why this test is supreme is because to its responsiveness, relevancy, and achievability. Schedule of PCR test in reference to symptoms, will restrict of detection. Sample gather site location is to be consider. New invention in RT-PCR to reverse are mainly centre on all sides, simple procedure, faster turnaround times, and reduce in the use of materials.

This is all about the RT-PCR Test and Cycle Threshold Value for determining if you are COVID-19 positive or not. For more information on covid-19, stay updated on our blog.